Volume 1
Number 2 July 2017Coronary Heart Disease with Diabetes: A Review Article
DOI: https://doi.org/10.70357/jdamc.2017.v0102.07
Wahab S M A1 , Ali S Y2 , Hossain S M D3 , Podder J K4 , Uddin R5
Abstract
There is a strong correlation between Coronary heart disease (CHD) and Diabetes mellitus (DM). There are complexrelationships between insulin and glucose homeostasis and the development of atherothrombotic vascular disease, andinvolves clustering of metabolic and procoagulant cardiovascular risk factors which, in turn, are underpinned by geneticpredisposition and genetic and environmental interactions. Diabetes is associated, not just with increased cardiovasculardisease, but also with a worse outcome. One reason for this appears to be enhanced myocardial dysfunction leading toaccelerated heart failure (diabetic cardiomyopathy) which predisposes patients to congestive heart failure. In fact, according tothe American Heart Association, it may be appropriate to say, 'diabetes is a cardiovascular disease'. So, it is very important toassess the cardiovascular risk of diabetic patients and to provide appropriate levels of advice and medication to control bloodglucose, blood pressure, lipids and other risk factors. Although tight glycemic control is essential, care should be taken to avoidtreatments known to exacerbate cardiovascular risk factors. In addition to therapeutic intervention, lifestyle changes are certainto be the most important regulators of insulin resistance, glucose control, and overall cardiovascular risk.
Keywords: Coronary Heart Disease, Diabetes, atherothrombotic vascular disease.
- Associate Professor, Department of Cardiology
- Professor and Head, Department of Cardiology
- Assistant Professor, Department of Cardiology
- Assistant Professor, Department of Cardiology
- Junior Consultant, Department of Cardiology