Volume 2
Number 2 July 2018Salivary Acetylcholine Concentration and Dementia: A Comparative Study in Dhaka City of Bangladesh
DOI: https://doi.org/10.70357/jdamc.2018.v0202.03
Kabir MA1 , Islam TB2 , Akhiruzzaman3 , Ferdous S4 , Parveen M5 , Sarker F6 , Akter H7
Abstract
This comparative cross sectional study was carried out to evaluate the relationship of salivary acetylcholine concentration with the events of dementia during the period of July 2014 to June 2015. For this study total 120 respondents were selected purposively. Among them 60 respondents were suffering from dementia (Diagnosed by medicine specialist) and rest 60 were without dementia selected as comparison group.
Out of all study subjects, mean(±SD) age of dementia patients was 73.10(±4.93) years with the age range of 62 to 84 years andthat of in comparative group was 71.20(±5.89) years with the age range of 64 to 85 years. Male (60.0%) was predominant indementia patients. The mean(±SD) value of Salivary acetylcholine in dementia group was found 153.93(±98.04) pg/ml andthat of in comparative group was 411.50(±112.50) pg/ml. Here Salivary acetylcholine was found lower in dementia patientsthan comparative group and therefore it can be concluded that salivary acetylcholine level can help to diagnose the risk ofdevelopment of early dementia.
Keywords: Dementia, Acetylcholine, Salivary acetylcholine, Bangladesh
- Assistant Professor, Department of Biochemistry
- Lecturer, Department of Biochemistry
- Assistant Professor, Department of Community Medicine
- Assistant Professor, Department of Biochemistry
- Assistant Professor Department of Biochemistry
- Assistant Professor, Department of Biochemistry
- Assistant Professor, Department of Oncology