Volume 5
Number 2 July 2021Ceftriaxone Utilization Pattern in Inpatient Department of Internal Medicine of a Tertiary Care Hospital
DOI: https://doi.org/10.70357/jdamc.2021.v0502.05
Yasmin S1 , Ahmed QSU2 , Rahman MM3 , Ela FA4
Abstract
Background: Antibiotic resistance becomes a global threat due to the rampant misuse and over use of antibiotics. Among themCeftriaxone is the most popular drug due its broad spectrum and low rates of toxicity and there is a prominent relationshipbetween the use of antimicrobial in hospital and its resistance. Therefore, close monitoring of ceftriaxone prescribing pattern isvery important to combat this resistance.
Objective: This study was conducted to identify the extent of Ceftriaxone use in internal medicine department of a tertiary carehospital.
Methods: A descriptive cross-sectional study was carried out through record review among 372 purposively selected patientsin internal medicine department of Dhaka Medical College from July 2018 to June 2019. All data were evaluated by WHOantibiotic guideline and BDNF and analyzed by SPSS.
Result: The proportion of Ceftriaxone use was 47.15%, RTI 10.22% was the most common indication for Ceftriaxone, 53.23%Ceftriaxone prescribed empirically, Metronidazole 22.67% was the most common co-administered drug, 22.58% prescriptionwas rational.
Conclusion: On the basis of the study findings it can be concluded that Ceftriaxone therapy is mostly empirical based.Respiratory tract infection is the common medical condition for ceftriaxone use. Metronidazole is the most commonlyprescribed co-administered antibiotic. Irrational use of ceftriaxone therapy is high.
Keywords: Ceftriaxone, Utilization pattern
- Assistant Professor and Head, Department of Pharmacology
- Classified Surgical Specialist
- Residential Medical Officer
- M.Phil. (Pharmacology)