Evaluation of HbA1c as A Dual Marker for Glycemic Status and Dyslipidemia in Type 2 Diabetes Mellitus

DOI: https://doi.org/10.70357/jdamc.2023.v0701.03

Shumon MUA1 , Begum R2 , Sultana N3 , Rahman MB4

Abstract

Patients with type 2 diabetes mellitus (T2DM) have a greater risk of development of dyslipidemia that is an important riskfactor for cardiovascular disease. The aim of the study is to investigate the role of HbA1c as a dual marker for glycemic statusand dyslipidemia in type 2 diabetes mellitus for early intervention to reduce cardiovascular and other complications and theirmortality, conducted in the department of Biochemistry Jalalabad Ragib- Rabeya medical college and hospital, Sylhet betweenthe period of October 2020 to September 2021. A total 290 diagnosed type 2 diabetic patients of both sexes were included in thisstudy. Three groups were made on the basis of their glycemic status. HbA1c, triglycerides, total cholesterol, HDL-cholesteroland LDL-cholesterol were measured in all three groups. Worst glycemic group showed statistically significant higher level oftriglycerides, total cholesterol and LDL-cholesterol. But HDL-cholesterol was almost same in all three groups. It is observedthat there is an association between HbA1C and some lipid parameters. Thus HbA1c is not only a useful biomarker of long termglycemic status but also can be a good predictor of lipid profile.

Keywords: Diabetes Mellitus, HbA C, Lipid profile, Dyslipidemia


  1. Assistant Professor, Department of Biochemistry

    Jalalabad Ragib-Rabeya Medical College, Sylhet

  2. Associate Professor, Department of Biochemistry

    Jalalabad Ragib-Rabeya Medical College, Sylhet

  3. Associate Professor, Department of Biochemistry Jalalabad

    Ragib-Rabeya Medical College, Sylhet

  4. Assistant Professor, Department of Biochemistry Jalalabad

    Ragib-Rabeya Medical College, Sylhet


Volume 7, Number 1 January 2023
Page: 9-13