Volume 8
Number 1 January 2024Non-Alcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus: A Global Problem Including Bangladesh Perspective
DOI: https://doi.org/10.70357/jdamc.2024.v0801.08
Akhinur1 , Sajib MSI2 , Bhunya AMY3 , SiddiqueMA4 , Rashid MH5
Abstract
Nonalcoholic fatty liver disease (NAFLD) is commonly associated with type 2 diabetes mellitus (type 2 DM). The global prevalence of NAFLD is rising and 70% of these patients have type 2 DM, obesity and insulin resistance. NAFLD progresses from simple steatosis to non-alcoholic steatohepatitis (NASH), cirrhosis of the liver and hepatocellular carcinoma. In BANGLADESH, the prevalence is the same. NAFLD prevalence is higher in the urban population, because of their lifestyle, obesity and increasing incidence of type 2 DM. Assessment and staging of disease are based on clinical parameters such as age, sex, BMI, liver function test, lipid profile and imaging modalities. In response to these threats, clinical care pathways for NAFLD and guidelines for metabolic dysfunction associated with fatty liver disease have been improved in developed countries. But in Bangladesh, pathways for NAFLD are still not developed. Several anti-diabetic agents have been evaluated for their potential hepatic benefits with some hopeful results. However, despite the wealth of knowledge in NAFLD and type 2 DM, lack of awareness of the disease and its consequences remains a major challenge, especially for clinicians. Because they may not be in the field of hepatology and gastroenterology. We proposed the urgent necessity of NAFLD management and awareness of NAFLD.
Keywords: Nonalcoholic fatty liver disease, type 2 diabetes mellitus, non-alcoholic steatohepatitis, cirrhosis of the liver, hepatocellular carcinoma.
- Assistant Registrar, Department of Medicine
- Registrar, Department of Medicine
- Assistant Registrar, Department of Medicine
- Registrar, Department of Medicine
- Professor of Department of Medicine